Inhibition of Transient Receptor Potential Vanilloid 6 channel, elevated in human ovarian cancers, reduces tumour growth in a xenograft model
Conclusion: TRPV6 mRNA and protein are elevated in biopsies of ovarian cancers compared to normal tissue. Inhibition of TRPV6 activity significantly reduces ovarian tumour growth providing evidence that TRPV6 is a feasible oncology target in ovarian cancers.
Source: Journal of Cancer - Category: Cancer & Oncology Authors: Hui Xue, Yuzhuo Wang, Tyson J. MacCormack, Tyler Lutes, Christopher Rice, Michelle Davey, Dominique Dugourd, T. Toney Ilenchuk, John M. Stewart Tags: Research Paper Source Type: research
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