MRI T2 signal intensity and tumor response in patients with GH-secreting pituitary macroadenoma: PRIMARYS post-hoc analysis.

Conclusions Patients with hypointense vs isointense GH-secreting macroadenomas had greater reductions in IGF-1 following primary treatment with lanreotide autogel, and were more likely to achieve tumor response. Assessment of T2 signal intensity at baseline may help to predict long-term responses to primary treatment with SSAs.
PMID: 30540560 [PubMed - as supplied by publisher]

Source: European Journal of Endocrinology - December 1, 2018 Category: Endocrinology Authors: Bonneville F, Rivière LD, Petersenn S, Bevan J, Houchard A, Sert C, Caron PJ Tags: Eur J Endocrinol Source Type: research