Extra-pleural solitary fibrous tumors: A review

Publication date: Available online 12 December 2018Source: The Egyptian Journal of Radiology and Nuclear MedicineAuthor(s): Nuno Almeida Costa, Diogo Fonseca, João SantosAbstractSolitary fibrous tumor (SFT) is a rare mesenchymal ubiquitous tumor reported in the pleura and a wide variety of extrapleural locations, most frequently in the orbits and extremities.Approximately 78–88% of SFTs are benign and 12–22% are malignant.Although tumor characteristics are highly dependent on the location there are unifying features in MR imaging suggesting SFT: well-circumscribed, often lobulated nodular lesion, delayed contrast enhancement and the presence of fibrous contents which are hypointense on T1 and T2-weighted MRI imaging.There are many SFT differential diagnosis, highly dependent to the tumor location. Due to its rarity the diagnosis of extrapleural SFTs may be challenging. Histopathologic analysis is always required to confirm the diagnosis and to allow the distinction between the benign and malignant forms.We review pleural and extrapleural SFTs, presenting diagnostic clues, differential diagnosis and prognostic factors.
Source: The Egyptian Journal of Radiology and Nuclear Medicine - Category: Nuclear Medicine Source Type: research