Impaired pressure natriuresis and non-dipping blood pressure in Rats with early type 1 diabetes mellitus.

In conclusion, functional impairment of renal sodium and BP homeostasis is an early manifestation of T1DM, preceding hypertension and nephropathy. Early intervention to restore pressure natriuresis in T1DM may complement reductions in cardiovascular risk achieved with glycaemic control. This article is protected by copyright. All rights reserved.
PMID: 30537108 [PubMed - as supplied by publisher]

Source: The Journal of Physiology - December 7, 2018 Category: Physiology Authors: Culshaw GJ, Costello HM, Binnie D, Stewart KR, Czopek A, Dhaun N, Hadoke PWF, Webb DJ, Bailey MA Tags: J Physiol Source Type: research