HOTAIR participates in hepatic insulin resistance via regulating SIRT1.

CONCLUSIONS: Upregulated HOTAIR promotes hepatic insulin resistance by inhibiting SIRT1 expression and AKT/GSK pathway. PMID: 30536334 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30536334?dopt=Abstract

Source: European Review for Medical and Pharmacological Sciences - December 13, 2018 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research