Effect of miR-21/TLR4/NF- κB pathway on myocardial apoptosis in rats with myocardial ischemia-reperfusion.

CONCLUSIONS: Myocardial I/R injury in rats leads to decreased expression of miR-21. The overexpression of miR-21 is able to effectively inhibit the TLR4/NF-κB pathway and reduce the level of myocardial apoptosis of rats and the release of inflammatory factors. PMID: 30536340 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research