Dynamic evaluation of hemostasis in the acute phase of Kawasaki disease using comprehensive coagulation functional assays

Kawasaki disease (KD) is a systemic vasculitis involving coronary arteries, sometimes resulting in aneurysms and myocardial infarction. Hyper-coagulability in the acute-phase of KD is indicated in some circumstances based on changes of individual clotting factors. Comprehensive coagulation assays, clot waveform analysis (CWA) and thrombin/plasmin generation assay (T/P-GA), have been developed to assess physiological hemostasis, but these techniques have not been applied in KD.

Source: Thrombosis Research - December 13, 2018 Category: Hematology Authors: Hiroyuki Yoshizawa, Keiji Nogami, Tomoko Matsumoto, Nobuyuki Tsujii, Toshiyuki Sakai, Toshio Takase, Ichiro Tanaka, Midori Shima Tags: Full Length Article Source Type: research