Small-conductance calcium-activated potassium current modulates the ventricular escape rhythm in normal rabbit hearts

The apamin-sensitive small-conductance calcium-activated K (SK) current IKAS modulates automaticity of the sinus node. IKAS blockade by apamin causes sinus bradycardia.

Source: Heart Rhythm - November 13, 2018 Category: Cardiology Authors: Juyi Wan, Mu Chen, Zhuo Wang, Thomas H. Everett, Michael Rubart-von der Lohe, Changyu Shen, Zhilin Qu, James N. Weiss, Penelope A. Boyden, Peng-Sheng Chen Source Type: research