Significant changes in circular RNA in the mouse cerebral cortex around an injury site after traumatic brain injury.

CONCLUSION: Many circRNAs are significantly up-regulated or down-regulated in the traumatic cerebral penumbra cortex after TBI. Among them, the circRNA chr8_87,859,283-87,904,548 potentially plays a pro-inflammatory role, which may have a deleterious effect on neurological restoration after TBI. .
PMID: 30529438 [PubMed - as supplied by publisher]

Source: Experimental Neurology - December 5, 2018 Category: Neurology Authors: Chen Z, Wang H, Zhong J, Yang J, Darwazeh R, Tian X, Huang Z, Jiang L, Cheng C, Wu Y, Guo Z, Sun X Tags: Exp Neurol Source Type: research