The onset of clinical manifestations in inflammatory bowel disease patients

CONCLUSION: Ulcerative colitis presented a high frequency of intestinal symptoms, and Crohn ’ s disease showed a high frequency of systemic manifestations at the onset of manifestation. There was a long delay in diagnosis, but individuals with more extensive disease and more obvious symptoms showed a shorter delay.RESUMO CONTEXTO: O diagn óstico da doença inflamatória intestinal é frequentemente retardado pela falta de capacidade para reconhecer as suas principais manifestações clínicas. OBJETIVO: Nosso estudo teve como objetivo descrever as manifestações clínicas iniciais em pacientes com doença inflamatória intestinal . MÉTODOS: Estudo transversal. Os pesquisadores obtiveram dados por entrevistas e registros médicos de pacientes com doença inflamatória intestinal em um centro de referência localizado na Bahia. RESULTADOS: Foram incluídos 306 pacientes. O tempo entre o início dos sintomas e o diagnósti co foi de 28 (±48) meses para doença de Crohn e 19 (±46) meses para colite ulcerativa. O tempo médio desde o início dos sintomas clínicos até o diagnóstico de doença de Crohn foi de 37 meses para pacientes com localização do ileocolon, 26 meses para a localização do íleo e 18 meses par a a localização do cólon. Nos do...
Source: Arquivos de Gastroenterologia - Category: Gastroenterology Source Type: research

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Authors: Abbassy AA, Trebinjac S, Kotb N Abstract Knee osteoarthritis is a degenerative "wear and tear" disorder affecting mainly population over 50 years old. It can also present in younger people, especially after an injury or as a part of other diseases. While many therapeutic options exist for knee osteoarthritis, none of them has the potential to cure this condition. Cellular Matrix represents a combination of natural non-crosslinked hyaluronic acid (HA), thixotropic cell separation gel, and sodium citrate anticoagulant solution. A combination of Cellular Matrix with autologous platelet-rich plasma (...
Source: Bosnian Journal of Basic Medical Sciences - Category: General Medicine Tags: Bosn J Basic Med Sci Source Type: research
Conclusions: There are several ongoing efforts to use novel ablative therapies directed towards the brain. The recent development of techniques that allow for precise targeting, accurate delivery of thermal doses and real-time visualization of induced tissue damage during the procedure have resulted in novel techniques for cerebral ablation such as magnetic resonance-guided focused ultrasound or laser interstitial thermal therapy. However, older techniques such as radiofrequency thermal ablation or stereotactic radiosurgery still have a pivotal role in the management of a variety of neurological disorders. PMID: 315371...
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
Authors: Tomasian A, Jennings JW Abstract Minimally invasive percutaneous thermal ablation of osseous metastases has proved safe and effective in management of selected patients with bone metastatic disease. These procedures have become a part of the treatment algorithm for certain subgroup of patients with osseous metastases to achieve pain palliation and/or local tumor control. This review details the armamentarium available and the most recent advances in minimally invasive, percutaneous image-guided thermal ablation for management of osseous metastases. PMID: 31537154 [PubMed - in process]
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
[Incontinence-associated dermatitis: a position paper]. Hautarzt. 2019 Sep 19;: Authors: Kottner J, Kolbig N, Bültemann A, Dissemond J Abstract Incontinence-associated dermatitis (IAD) describes damage to the skin caused by repeated and prolonged contact with urine and/or feces. Patients of all ages can be affected; the diagnosis is preferably used in adults and adolescents. The predilection sites are perineal, perianal, the inner thighs and the convex areas of the buttocks. Increased moisture on the skin surface, increased pH, occlusion, feces digestive enzymes and repeated skin cleansing pr...
Source: Der Hautarzt: Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete - Category: Dermatology Tags: Hautarzt Source Type: research
ConclusionIn a referral center in Salvador city, socio-economic problems were the main factors associated with ED. Psychological impact of poor social conditions should be routinely assessed in patients with ED to implement preventive measures for ED.
Source: The Brazilian Journal of Infectious Diseases - Category: Infectious Diseases Source Type: research
Publication date: Available online 20 September 2019Source: The Brazilian Journal of Infectious DiseasesAuthor(s): Alejandra Cañas-Arboleda, Catalina Hernández-Flórez, Javier Garzón, Claudia Marcela Parra-Giraldo, Juan Felipe Burbano, José Enrique Cita-PardoAbstractExposure to Pneumocystis jirovecii (P. jirovecii) can lead to a wide variety of presenting features ranging from colonization in immunocompetent patients with lung disease, to invasive infections in immunocompromised hosts. Colonization by this fungus in patients with chronic obstructive pulmonary disease (COPD) could be associ...
Source: The Brazilian Journal of Infectious Diseases - Category: Infectious Diseases Source Type: research
Flibanserin can help women shed up to five per cent of body weight. In a study, a quarter of post-menopausal women taking the drug lost weight - three times as many as those in a placebo group.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Authors: Meditskou S, Grekou A, Toskas A, Papamitsou T, Miliaras D Abstract Pyloric type metaplasia (PYME) as evidence of chronic mucosal damage, is one of the main histopathological findings for diagnosing Crohn's Disease (CD) in terminal ileum biopsies, according to the latest guidelines but still frequently underdiagnosed in routine pathology. Foveolar metaplasia (FOME) changes in mucosa, another aspect of the chronic post -inflammatory Ulcer Associated Cell Lineage (UACL), have only been reported in a few cases. However, their clinical significance has not been investigated in depth except in pouchitis. The aim...
Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research
I was out of work for 31 days, from August 16 until September 17. The reason is because I had surgery on my left knee, an arthroscopy of the medial meniscus. It got damaged somehow; the cause is unknown to me. It started becoming problematic sometime around Christmas 2018, but I didn’t really pay much attention to it. I figured it had to be something fairly minor which would resolve itself. However, it didn’t. And ultimately it led to my being evaluated by an orthopedic surgeon, having to get X-Rays and Magnetic Resonance Imaging on my knee, and finally having the surgical procedure performed to fix the problem...
Source: Qui Interrogat - Category: Nursing Authors: Tags: Uncategorized Source Type: blogs
This study was carried out with samples belonging to 140 horses residing in Spain and showing common clinical signs of EP. A blood smear microscopic examination and a comparison between the different results obtained by competitive Enzyme-Linked Immunosorbent Assay (cELISA), real-time Polymerase Chain Reaction (PCR) and hematological and biochemical (direct and total bilirubin) screening were conducted. EP positivity rates by cELISA and PCR were 50.7% and 42.9%, respectively, whereas only 9% of the horses were positive in the microscopic analysis. A significantly higher number of B. caballi-positive horses were detected by...
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
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