Expression Levels of microRNAs miR-93 and miR-200a in Pancreatic Adenocarcinoma with Special Reference to Differentiation and Relapse-Free Survival.

CONCLUSIONS: High miR-93 and miR-200a levels in cancer cells of PDAC were associated with better differentiation, and miR-200a expression in benign tissue with excellent RFS. Keap1 and Nrf2 mRNA levels showed prominent down-regulation in cancerous versus benign tissue, but they were not associated with disease aggressiveness or outcome.
PMID: 30537722 [PubMed - as supplied by publisher]

Source: Oncology - December 11, 2018 Category: Cancer & Oncology Authors: Karihtala P, Porvari K, Soini Y, Eskelinen M, Juvonen P, Haapasaari KM Tags: Oncology Source Type: research