WFSBP guidelines on how to grade treatment evidence for clinical guideline development.

WFSBP guidelines on how to grade treatment evidence for clinical guideline development.
World J Biol Psychiatry. 2018 Dec 11;:1-28
Authors: Hasan A, Bandelow B, Yatham LN, Berk M, Falkai P, Möller HJ, Kasper S, WFSBP Guideline Task Force Chairs
Abstract
This manuscript reviews sources of data typically used in guideline development, available grading systems, their pros and cons, and the methods for evaluating risks of bias in publications, and proposes a revised method for grading evidence and recommendations for use in development of clinical treatment guidelines. The new World Federation of Societies of Biological Psychiatry (WFSBP) grading system allows guideline developers to follow a multi-step approach of defining Levels of Evidence (LoE), applying criteria for grading (define the acceptability) and the Grading of Recommendations (GoR). Further, these updated WFSBP recommendations for rating evidence and treatment recommendations provide a grading system that takes into account potential biases in sources of evidence in arriving at final ratings that are likely more clinically meaningful and pragmatic and thus should be used for the development of future treatment guidelines.
PMID: 30526182 [PubMed - as supplied by publisher]

Source: The World Journal of Biological Psychiatry - December 11, 2018 Category: Psychiatry Authors: Hasan A, Bandelow B, Yatham LN, Berk M, Falkai P, Möller HJ, Kasper S, WFSBP Guideline Task Force Chairs Tags: World J Biol Psychiatry Source Type: research