Low serum phosphate and magnesium levels are associated with peripheral neuropathy in patients with type 2 diabetes mellitus

Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes [1], occurs in approximately 50% of patients with diabetes [2]. DPN is also a significant independent risk factor for diabetic foot ulcers, which is the major course of lower extremity amputation in patients with diabetes [3]. Several risk factors have been identified for the development of DPN, including chronic hyperglycemia [4], oxidative stress [5], inflammation [6] and accumulation of advanced glycation end products [7].
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research