Biosynthesis of an anti-tuberculosis sesterterpenoid asperterpenoid A

Org. Biomol. Chem., 2018, Accepted Manuscript DOI: 10.1039/C8OB02832J, CommunicationJia-Hua Huang, Jian-Ming Lv, Qiao-Zhen Wang, Jian Zou, Yongjun Lu, Qing-Lin Wang, Dongni Chen, Xin-Sheng Yao, Hao Gao, Dan Hu A putative three-gene cluster for asperterpenoid A was identified. Step-wise reconsitution of this gene cluster in Aspergillus oryzae reveals that astC encodes a sesterterpene cyclase to synthesize preasperterpenoid A, which... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - December 11, 2018 Category: Molecular Biology Authors: Jia-Hua Huang Source Type: research