Reduced Variability in Tacrolimus Pharmacokinetics Following Intramuscular Injection Compared to Oral Administration in Cynomolgus Monkeys: Investigating Optimal Dosing Regimens

In this study, we found that the pharmacokinetic characteristics of tacrolimus were more constant following IM injection compared with oral administration. These results suggest that IM injection can be an alternative route of administration fin non-human primate model studies.
Source: Journal of Pharmacological Sciences - Category: Drugs & Pharmacology Source Type: research