Evaluation of the effect of hesperidin on vascular endothelial growth factor gene expression in rat skin animal models following cobalt-60 gamma irradiation
Conclusions: We can conclude that hesperidin is a potent angiogenic factor. Hesperidin as a radioprotector can initiate angiogenesis by VEGF gene induction. It may stimulate epithelialization, collagen deposition, and enhanced cellular proliferation. These changes can together accelerate wound healing, in particular, radiation-induced skin damage.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Gholamhassan Haddadi Akbar Abbaszadeh Mohammad Amin Mosleh-Shirazi Mohammad Ali Okhovat Ashkan Salajeghe Zhila Ghorbani Source Type: research
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