Network strategy to investigate differential pathways in sporadic amyotrophic lateral sclerosis
Conclusion: We have investigated 217 differential pathways and 21 significant differential pathways between SALS and normal controls based on network strategy. The findings might provide potential biomarkers for detection and therapy of SALS clinically and give great insights to reveal molecular mechanism underlying this disease. However, how these pathways cooperated with each other is still not clear, and future study should focus on this aspect.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Li-Hong Han Xiao-Yan Fan Hong Guo Wei Wei Mao-Meng Chen Shu-Fang Yan Source Type: research