[ASAP] Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.8b00909

Source: Journal of Medicinal Chemistry - December 10, 2018 Category: Chemistry Authors: Yangbing Li, Jiuling Yang, Angelo Aguilar, Donna McEachern, Sally Przybranowski, Liu Liu, Chao-Yie Yang, Mi Wang, Xin Han, Shaomeng Wang Source Type: research