Impact of zinc uptake regulator Zur on the sensitivity and oxidative stress response of Acinetobacter baumannii to antibiotics

Acinetobacter baumannii is a Gram-negative and opportunistic pathogen responsible for nosocomial infections including pneumonia, urinary tract infections, burn infections, secondary meningitis and systemic infections [1]. Ever increasing rates of resistance to antibiotics [2 –5] make A. baumannii a significant human pathogen with critical needs for new antibiotic development [6]. Its ability to tolerate desiccation and disinfection [7] and to form biofilms [8] contribute to morbidity and mortality [3].
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Source Type: research