The MAGI2 gene polymorphism rs2160322 is associated with Graves ’ disease but not with Hashimoto’s thyroiditis

ConclusionsOur study identified thatMAGI2 rs2160322 was strongly associated with GD susceptibility. The potential dysfunction of tight junction proteins and aberrant epithelial barrier caused by abnormalMAGI2 expression may be a novel mechanism of GD.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research