Nail Psoriasis: An Updated Review and Expert Opinion on Available Treatments, Including Biologics.

Nail Psoriasis: An Updated Review and Expert Opinion on Available Treatments, Including Biologics.
Acta Derm Venereol. 2018 Dec 06;:
Authors: Bardazzi F, Starace M, Bruni F, Magnano M, Piraccini BM, Alessandrini A
Abstract
Nail psoriasis affects 50-79% of patients with skin psoriasis and up to 80% of patients with psoriatic arthritis, and can also represent a negative prognostic factor in individuals with plaque psoriasis. Treatments for nail psoriasis are limited, as nails are often difficult to treat with topical therapies alone, and relapse is common. Among different systemic agents, secukinumab, a fully human monoclonal antibody targeting interleukin (IL)-17A, is the only antibody supported by a trial specifically conducted in patients with nail psoriasis (the TRANSFIGURE trial) and has the longest follow-up available to date. In this setting, secukinumab is characterized by the highest efficacy at week 16. This review analysed the different therapeutic options for nail psoriasis, focusing on new treatments that have shown promising results in this field.
PMID: 30521057 [PubMed - as supplied by publisher]

Source: Acta Dermato-Venereologica - December 6, 2018 Category: Dermatology Authors: Bardazzi F, Starace M, Bruni F, Magnano M, Piraccini BM, Alessandrini A Tags: Acta Derm Venereol Source Type: research