Chronic stress exposure and daily stress appraisals relate to biological aging marker p16INK4a

An emergent literature suggests that exposure to adverse social conditions is associated with accelerated biological aging, offering one mechanism through which adversity may increase risk for age-related diseases, including diabetes, atherosclerosis, neurodegeneration, and cancer. Chronic stress, via prolonged or repeated activation of the sympathoadrenal system, is thought to increase disease risk through its cumulative impact on key biological aging pathways (Epel, 2009; Robles and Carroll, 2011; Shalev et al., 2014).

Source: Psychoneuroendocrinology - December 7, 2018 Category: Psychiatry Authors: Kelly E. Rentscher, Judith E. Carroll, Rena L. Repetti, Steven W. Cole, Bridget M. Reynolds, Theodore F. Robles Source Type: research