Prevalence of macrolide resistance in Treponema pallidum is associated with macrolide consumption.

Prevalence of macrolide resistance in Treponema pallidum is associated with macrolide consumption.
J Med Microbiol. 2018 Dec 06;:
Authors: Kenyon C
Abstract
We hypothesized that the large global variations in the prevalence of macrolide resistance in Treponema pallidum are related to differences in population-level macrolide consumption. The hypothesis was tested by, at a country-level, regressing the peak prevalence of macrolide resistance against the national macrolide consumption in the year prior to this, controlling for the year of the resistance prevalence estimate. A strong association was found between the per capita consumption of macrolides and macrolide resistance (coefficient 0.7, 95 % confidence interval 0.2-0.12, P=0.009).
PMID: 30520715 [PubMed - as supplied by publisher]

Source: Journal of Medical Microbiology - December 6, 2018 Category: Microbiology Authors: Kenyon C Tags: J Med Microbiol Source Type: research