Africa: To Beat Cholera, What Is Most Needed Is a Reliable Drinking Water Supply

This article is co-authored by Aur élie Jeandron, Martin Leménager, Damien Machuel, Baron Bashige Rumedeka, Jaime Mufitini Saidi and Oliver Cumming.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news

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[Thomson Reuters Foundation] Nairobi -At least half a million survivors of a powerful cyclone in southeast Africa are at risk of fatal diseases, from cholera and dysentery to malaria, aid workers warned on Thursday, as rescue teams struggled to reach flood-hit communities.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Faraday Discuss., 2019, Accepted Manuscript DOI: 10.1039/C9FD00017H, PaperClare Mahon, Gemma C. Wildsmith, Diksha Haksar, Eyleen de Poel, Roland Pieters, Jeffrey M. Beekman, Michael Webb, W Bruce Turnbull Stimuli-responsive receptors for the recognition unit of the cholera toxin (CTB) have been prepared by attaching multiple copies of its natural carbohydrate ligand, the GM1 oligosaccharide, to a thermoresponsive polymer... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Faraday Discuss. latest articles - Category: Chemistry Authors: Source Type: research
Journal of the American Chemical SocietyDOI: 10.1021/jacs.8b11480
Source: Journal of the American Chemical Society - Category: Chemistry Authors: Source Type: research
AbstractPurpose of ReviewInfectious diseases are a risk when traveling internationally, and it is important to know the potential disease burden of a region and take appropriate preventative actions before traveling. For individuals with HIV, there are special considerations and contradictions for various vaccines and medications as well as interactions with likely antiviral drugs. The purpose of this review is to summarize the vaccine and medication recommendations for travelers with HIV infection. We also review recent studies to update these recommendations.Recent FindingsThe recommendation for yellow fever vaccine has ...
Source: Current Infectious Disease Reports - Category: Infectious Diseases Source Type: research
In this study, we used silkworm pupae to develop a safer vaccine for Alzheimer’s disease (AD) patients. Aβ15 peptide was fused with the cholera toxin B subunit (CTB) and expressed in silkworm pupae. Then, we tested an oral vaccine with the peptide expressed by silkworm pupae in a transgenic mouse model of AD. The results show that anti-Aβ antibodies were induced, Aβ deposition in the brain decreased, the content of malondialdehyde was lower than in the other group, and memory and cognition of the mice improved. These results suggest that the high-nutrient CTB-Aβ15 silkworm pupa vaccine has ...
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research
Abstract A comprehensive targeted intervention (CTI) was designed and deployed in the neighborhoods of cholera cases in the Kathmandu Valley with the intent of reducing rates among the neighbors of the case. This was a feasibility study to determine whether clinical centers, laboratories, and field teams were able to mount a rapid, community-based response to a case within 2 days of hospital admission. Daily line listings were requested from 15 participating hospitals during the monsoon season, and a single case initiated the CTI. A standard case definition was used: acute watery diarrhea, with or without vomiting...
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research
Conclusion: The results clearly indicated that V. officinalis AgNPs have potential antimicrobial activity against Gram-positive and Gram-negative bacteria. PMID: 30873268 [PubMed]
Source: Iranian Journal of Microbiology - Category: Microbiology Tags: Iran J Microbiol Source Type: research
International non-government organisations (INGOs) in Yemen strongly condemn the horrific attacks in Hajjah governorate on Sunday which according to the UN killed 22 people – twelve women and ten children – and injured many more. Hajjah has seen an increase in tensions and fighting in recent weeks; thousands of people have been displaced from their homes and are in need of humanitarian aid and many more are reportedly trapped by the fighting and cannot flee to safety or reach help. These horrific incidents show that innocent civilians including children continue to pay the price for a conflict in which they hav...
Source: Doctors of the World News - Category: International Medicine & Public Health Authors: Tags: Uncategorised Source Type: news
(PLOS) Recently, the sensitivity of fecal microbiological cultures for detecting cholera has come under question. Researchers reporting in PLOS Neglected Tropical Diseases investigated this claim using a 'vaccine probe' analysis of a completed cholera vaccine cluster randomized trial to support the sensitivity of conventional microbiological culture for cholera.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
by Justin Im, Md. Taufiqul Islam, Faisal Ahmmed, Deok Ryun Kim, Yun Chon, K Zaman, Ashraful Islam Khan, Mohammad Ali, Florian Marks, Firdausi Qadri, John D. Clemens Analyses of stool from patients with acute watery diarrhea (AWD) using sensitive molecular diagnostics have challenged whether fecal microbiological cultures have acceptably high sensitivity for cholera diagnosis. If true, these findings imply that current estimates of the global burden of cholera , which rely largely on culture-confirmation, may be underestimates. We conducted a vaccine probe study to evaluate this possibility, assessing whether an effective ...
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research
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