Faulty sensing: Cellular energy sensor linked to the progression of chronic kidney disease

(Tokyo Medical and Dental University) Chronic kidney disease (CKD) is associated with energy depletion in kidney cells, resulting in reduced kidney function. Researchers at TMDU and Kyushu University found that failure of an important cellular energy sensor to detect energy depletion is key to the progression of CKD. However, by stimulating the activity of the sensor using alternative methods, the researchers could halt CKD progression and repair some of the tissue damage. This mechanism therefore represents a novel therapeutic target.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news