Faulty sensing: Cellular energy sensor linked to the progression of chronic kidney disease

(Tokyo Medical and Dental University) Chronic kidney disease (CKD) is associated with energy depletion in kidney cells, resulting in reduced kidney function. Researchers at TMDU and Kyushu University found that failure of an important cellular energy sensor to detect energy depletion is key to the progression of CKD. However, by stimulating the activity of the sensor using alternative methods, the researchers could halt CKD progression and repair some of the tissue damage. This mechanism therefore represents a novel therapeutic target.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
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