Pituitary 18F-FDG uptake correlates with serum TSH levels in thyroid cancer patients on 18F-FDG PET/CT

The objective of this study was to evaluate the relationship between fluorine-18-fluorodeoxyglucose (18F-FDG) uptake in the pituitary gland and serum thyroid-stimulating hormone (TSH) levels in differentiated thyroid cancer (DTC) patients on 18F-FDG PET/computed tomography (CT). Patients and methods A total of 215 DTC patients and 215 age-paired and sex-paired healthy screening participants were included. DTC patients were divided into hypothyroid, euthyroid and subclinical hyperthyroid patients according to their serum TSH levels. The relationship between 18F-FDG uptake in the pituitary gland and serum TSH levels was evaluated the in DTC patients, and the pituitary 18F-FDG metabolism was compared in different thyroid status. Results The standardized uptake value of pituitary (SUVp) in all 430 patients was directly correlated with serum TSH levels (r=0.479 and 0.432, all P
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: ORIGINAL ARTICLES Source Type: research