Altered Hypothalamus-Pituitary-Adrenal Axis Function: A Relevant Factor in the Comorbidity of Atopic Eczema and Attention Deficit/Hyperactivity Disorder?

Atopic eczema (AE) is a chronic inflammatory skin disease with key symptoms such as eczematous and inflammatory eruptions of the skin and intense pruritus (Brown, 2016; Lawton, 2014). AE typically manifests in early infancy (with an onset before the age of 5 in 90% of the patients) and represents one of the most common chronic childhood disorders (Weidinger and Novak, 2016). Notably, about 50% of all individuals with AE have specific allergic sensitization indicating that atopy is not a necessary feature of AE (Flohr et al., 2004).

Source: Psychoneuroendocrinology - December 7, 2018 Category: Psychiatry Authors: A. Buske-Kirschbaum, K. Trikojat, F. Tesch, J. Schmitt, V. Roessner, H. Luksch, A. Roesen-Wolff, F. Plessow Source Type: research