[Effect of acupuncture on TGF- β1/Smads pathway in mice with airway remodeling mic].

CONCLUSIONS: Acupuncture can inhibit airway remodeling by inhibiting the expression of airway TGF-β1 and down-regulating the expression of Smads and α-SMA to reduce airway inflammatory response. Airway expressions of type-Ⅰ and Smads proteins remain high after inhibiting TGF-β1. Acupuncture may control asthma progression through the TGF-β1/Smads pathway.
PMID: 30514688 [PubMed - in process]

Source: Journal of Southern Medical University - November 30, 2018 Category: Universities & Medical Training Authors: Liu H, Liu J, Peng M, Li Y, Li C Tags: Nan Fang Yi Ke Da Xue Xue Bao Source Type: research