Pharmacokinetics and biodistribution of polymeric micelles containing miRNA and small-molecule drug in orthotopic pancreatic tumor-bearing mice

Conclusion: PEG-b-PCC-g-DC-g-TEPA micelles carrying GDC-0449 and let-7b mimic have great potential to improve drug delivery for pancreatic cancer treatment.

Source: Theranostics - December 7, 2018 Category: Molecular Biology Authors: Virender Kumar, Vaibhav Mundra, Yang Peng, Yingzhe Wang, Chalet Tan, Ram I. Mahato Tags: Research Paper Source Type: research