A circular transcript of ncx1 gene mediates ischemic myocardial injury by targeting miR-133a-3p

Conclusions: Our findings reveal a novel regulatory pathway that comprises circNCX1, miR-133a-3p and CDIP1, that is involved in cardiomyocyte apoptosis. This pathway may serve as a potential therapeutic avenue for ischemic heart diseases.

Source: Theranostics - December 7, 2018 Category: Molecular Biology Authors: Mengyang Li, Wei Ding, Muhammad Akram Tariq, Wenguang Chang, Xuejuan Zhang, Wenhua Xu, Lin Hou, Yifei Wang, Jianxun Wang Tags: Research Paper Source Type: research