Corindus touts first-in-human coronary telerobotics study with CorPath system

Corindus Vascular Robotics (OTC:CVRS) today touted that its CorPath robotic surgical platform was used in a first-in-human telerobotic intervention study in India. The Waltham, Mass.-based company touted that the study was the world’s first percutaneous coronary intervention conducted from a remote location outside of a catheterization lab. In the trial, five patients at India’s Apex Heart Institute underwent an elective PCI procedure from a distance of approximately 20 miles away, Corindus said. The procedures were performed by Apex Heart Institute chair and chief interventional cardiologist Dr. Tejas Patel from inside the Swaminarayan Akshardham temple in Gandhinagar, while his partner, Dr. Sanjay Shah, attended to the patient in person at the Apex Heart Institute. “The first in human cases of remote robotic PCI represent a landmark event for interventional medicine. The application of telerobotics in India has the potential to impact a significant number of lives by providing access to care that may not otherwise have been possible. For the first time in cardiology’s history, India will shine for this ground-breaking innovation, and I am honored to be a part of this historic occasion,” Dr. Patel said in a prepared statement. Corindus said that following the study, it plans to begin commercial product development to allow the CorPath system to be used in remote interventions. “Cardiovascular disease, including stroke, is the world&rs...
Source: Mass Device - Category: Medical Devices Authors: Tags: Cardiovascular Clinical Trials Featured Robotics Corindus Vascular Robotics Source Type: news

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In conclusion, this is the first report to show that pyroptotic cell death occurs in the aging brain and that the inflammasome can be a viable target to decrease the oxidative stress that occurs as a result of aging. Reducing Levels of Protein Manufacture Slows Measures of Aging in Nematodes https://www.fightaging.org/archives/2018/12/reducing-levels-of-protein-manufacture-slows-measures-of-aging-in-nematodes/ Researchers here demonstrate that an antibiotic slows aging in nematode worms, providing evidence for it to work through a reduction in protein synthesis. Beyond a slowing of aging, one of the con...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
5'-AMP-activated protein kinase (AMPK), a member of the serine/threonine (Ser/Thr) kinase group, is universally distributed in various cells and organs. It is a significant endogenous defensive molecule that responds to harmful stimuli, such as cerebral ischemia, cerebral hemorrhage, and, neurodegenerative diseases (NDD). Cerebral ischemia, which results from insufficient blood flow or the blockage of blood vessels, is a major cause of ischemic stroke. Ischemic stroke has received increased attention due to its '3H' effects, namely high mortality, high morbidity, and high disability. Numerous studies have revealed that act...
Source: Theranostics - Category: Molecular Biology Authors: Tags: Review Source Type: research
AbstractObjectivesTo describe the epidemiology and clinical heterogeneity of Guillain –Barré syndrome (GBS) in Denmark and to compare a population-based cohort to prospectively included patients in the International GBS Outcome Study (IGOS).MethodsThe incidence rate (IR) of GBS in Denmark from September 2012 to December 2015, applying the National Institute of Neurological Disorders and Stroke (NINDS) diagnostic criteria, was estimated and the level of diagnostic certainty was described with the Brighton criteria. All cases registered with a diagnosis of GBS or other inflammatory neuropathies in the Danish Nat...
Source: Journal of Neurology - Category: Neurology Source Type: research
Stroke is a leading cause of death and disability around the world. In the United States alone, nearly 800,00 people suffer from a stroke each year. Many of those who are lucky to survive continue to live with various long-term physical disabilities,...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Neurology Rehab Source Type: blogs
Abstract Stroke is the result of blockage or rupture of blood vessels in the brain and is the leading cause of death and disability in the world. Currently only a very limited number of therapeutic approaches are available for treatment of stroke patients, and the vast majority of neuroprotective agents that tested positively in pre-clinical studies failed in clinical trials. In recent years, the clinical value of the use of exosomes for stroke treatment has received widespread attention due their unique characteristics such as low immunogenicity, low toxicity and biodegradability, ability to cross the blood-brain...
Source: Cell Transplantation - Category: Cytology Authors: Tags: Cell Transplant Source Type: research
CONCLUSIONS: The present study shows that pseudopterosin A attenuates neuronal injury in the pMCAO model by acting on the Akt signalling pathway. PMID: 30509030 [PubMed - in process]
Source: Folia Neuropathologica - Category: Pathology Authors: Tags: Folia Neuropathol Source Type: research
This is a note of a temporary expression of concern related to the publication titled “Effect of immobilization upon renal synthesis of 1,25‑dihydroxyvitamin D in disabled elderly stroke patients” by Y Sato, K Oizumi, H Kuno, M Kaji (Bone. 1999 March; 24(3): 271–275. doi: https://doi.org/10.1016/S8756-3282(98)00185-9).
Source: Bone - Category: Orthopaedics Tags: Expression of Concern Source Type: research
Conclusions: Despite fulfilling majority of the general evaluation and aphasia-specific evaluation criteria, the highest rated program was still found to be unsuitable for people with poststroke aphasia. Thus, e-mental health programs require substantial redevelopment if they are likely to be useful to people with poststroke aphasia.
Source: Journal of Medical Internet Research - Category: General Medicine Authors: Source Type: research
CONCLUSIONS: This study highlights the perceived negative consequences of falls amongst people with stroke, and the potential contribution of falls to the reduced levels of physical activity often seen following a stroke. Our findings emphasise the need to address falls and balance related self-efficacy alongside strategies to promote safe mobility. A paradigm shift may be needed to highlight potentially modifiable intrinsic risk factors and emphasise the relevance and value of proactive fall prevention to people with stroke. Implications for rehabilitation People with stroke may not report falls or may minimise their sign...
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Tags: Disabil Rehabil Source Type: research
Publication date: Available online 2 December 2018Source: NeuroscienceAuthor(s): Yimei Yuan, Zhaoguang Zhang, ZhenGang Wang, Liu JinlanAbstractStroke is a leading cause of mortality and serious disability worldwide with limited treatment options. Angiogenesis has been reported to involved in post-stroke recovery. Although the molecular mechanisms that regulate angiogenesis remain ambiguous, microRNAs have emerged as effective regulators of angiogenesis, involved in neurological function outcome. The present study aims to investigate the regulatory effects of miRNA-27b on post-stroke angiogenesis. In primary cultured brain ...
Source: Neuroscience - Category: Neuroscience Source Type: research
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