Subclonal TP53 copy number is associated with prognosis in multiple myeloma

We present a framework for identifying subclonal TP53 deletions by MLPA, to improve patient stratification in MM and tailor therapy, enabling management strategies.

Source: Blood - December 6, 2018 Category: Hematology Authors: Shah, V., Johnson, D. C., Sherborne, A. L., Ellis, S., Aldridge, F. M., Howard-Reeves, J., Begum, F., Price, A., Kendall, J., Chiecchio, L., Savola, S., Jenner, M. W., Drayson, M. T., Owen, R. G., Gregory, W. M., Morgan, G. J., Davies, F. E., Houlston, R. Tags: Multiple Myeloma, Lymphoid Neoplasia, Brief Reports, Clinical Trials and Observations Source Type: research