Assessment of Hedgehog Signaling Pathway for Bone Regeneration in a Rat Mandibular Defect

This animal model study investigates whether a biosynthetic bone graft cross-linked with smoothened agonist activates the hedgehog signaling pathway in the reconstruction of craniofacial bony defects in female rats and if this is associated with bone regeneration.
Source: JAMA Facial Plastic Surgery - Category: Cosmetic Surgery Source Type: research