Silicosis is on the rise, but is there a therapeutic target?

(CNRS) Researchers from the CNRS, the University of Orl é ans, and the company Artimmune, in collaboration with Turkish clinicians from Atat ü rk University, have identified a key mechanism of lung inflammation induced by silica exposure, which leads to silicosis, an incurable disease. Their study in mice and patients, published in Nature Communications, shows that this inflammation can be prevented by extracellular DNA degradation, suggesting a new therapeutic target.

Source: EurekAlert! - Biology - December 6, 2018 Category: Biology Source Type: news