Immune adaptor protein SKAP1 (SKAP-55) forms homodimers as mediated by the N-terminal region

Immune cell adaptor protein SKAP1 couples the antigen-receptor (TCR/CD3) with the activation of LFA-1 adhesion in T-cells. Previous work by ourselves and others have shown that SKAP1 can directly bind to other...

Source: BMC Research Notes - December 6, 2018 Category: Research Authors: Monika Raab, Klaus Strebhardt and Christopher E. Rudd Tags: Research note Source Type: research