Subcutaneous spacer injection to reduce skin toxicity in breast brachytherapy: A pilot study on mastectomy specimens

Accelerated partial breast irradiation is a treatment option for selected patients with early-stage breast cancer. Some accelerated partial breast irradiation techniques lead to skin toxicity with the skin dose as a main risk factor. Biodegradable spacers are effective and safe in prostate brachytherapy to protect the rectum. We hypothesize that a subcutaneous spacer injection reduces the skin dose in breast brachytherapy.

Source: Brachytherapy - December 5, 2018 Category: Cancer & Oncology Authors: Gerson M. Struik, Jean-Philippe Pignol, Inger-Karine Kolkman-Deurloo, Jeremy Godart, Gerda M. Verduijn, Linetta B. Koppert, Erwin Birnie, Ali Ghandi, Taco M. Klem Source Type: research