Attempted use of PACE for riboswitch discovery generates three new translational theophylline riboswitch side products

The purpose of this project was to use an in vivo method to discover riboswitches that are activated by new ligands. We employed phage-assisted continuous evolution (PACE) to evolve new riboswitches in vivo. W...

Source: BMC Research Notes - December 5, 2018 Category: Research Authors: Zachary M. Shaver, Stephanie S. Bent, Steven R. Bilby, Michael Brown, Anna Buser, Itzayana G. Cuellar, Athena J. Davis, Lindsay Doolan, Fatima C. Enriquez, Autumn Estrada, Shelby Herner, J. Cody Herron, Andrew M. Hunn, Madison Hunter, Hartlee Johnston, Ow Tags: Research note Source Type: research