The Atomizer and Naloxone: Life-Saving Treatment for Opioid ODs

​The atomizer is a handy tool to instill life-saving medication into the nose, and you should consider stocking them if you don't already. An atomizer can be used to administer naloxone and countless other drugs as well as for moderate sedation and pain control. Pediatric and adult patients alike can benefit from intranasal fentanyl or Versed. Studies on intranasal epinephrine for anaphylaxis also look promising, but it does require a higher dose—5 mg instead of 0.3 mg. (Asian Pac J Allergy Immunol 2016;34[1]:38; http://bit.ly/2Prpjhb.)The atomizer is easy to use and can be attached to any syringe. Each spray creates a fine mist, which can penetrate the mucus membranes. You can administer about 0.5-1 mL of fluid per pump. Keep in mind the dosage of intranasal medications is often higher than that of IM, IV, and oral doses.Dr. James Roberts demonstrates the use of a traditional atomizer.Three 1 mL syringes with standard-sized atomizers. Photo by M. Roberts.Opioid StruggleMore than 33,000 people died from opioid overdoses in 2015, including prescription pain relievers, heroin, and fentanyl. (National Institute on Drug Abuse. http://bit.ly/2PrdY0D.) Naloxone is a nonselective and competitive opioid receptor antagonist, and reverses central nervous system depression caused by opioids. It can be used intravenously, intramuscularly, intranasally, and even nebulized.Naloxone has been around for almost 50 years. It is well researched, well studied, and abundantly used. The dr...
Source: The Procedural Pause - Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

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This study will provide a theoretical basis for industrial applications of modified yam starch.
Source: LWT Food Science and Technology - Category: Food Science Source Type: research
Publication date: December 2019Source: Food Packaging and Shelf Life, Volume 22Author(s): Manokaran Vadivel, Murugesan Sankarganesh, Jeyaraj Dhaveethu Raja, Jegathalaprathaban Rajesh, Dhanuskodi Mohanasundaram, Muthukaruppan AlagarAbstractThe prime objective of the present study is to develop a biodegradable food packaging hybrid film materials from renewable sources. Polyvinyl alcohol (PVA), chitosan (CS), xylan (CC) and hydroxyapatite (nHA) were used as the sources of bio-degradable polymer and curcumin (Cur) as antioxidant agent to prepare an intelligent packaging PVA/CS/CC/nHA hybrid film (PCC) to assess the fish fresh...
Source: Food Packaging and Shelf Life - Category: Food Science Source Type: research
Conclusions: High screen time was the most prevalent lifestyle risk behavior independently associated with depressive symptoms. Multiple lifestyle changes and improvement of appearance satisfaction should be included in measures targeting adolescents for the prevention and treatment of depressive symptoms. Future studies should elaborate on the gender differences in other adolescent age groups. Appearance satisfaction should be acknowledged as an important confounder in future studies of lifestyle and depressive symptoms. PMID: 31419392 [PubMed - as supplied by publisher]
Source: Nordic Journal of Psychiatry - Category: Psychiatry Tags: Nord J Psychiatry Source Type: research
Publication date: Available online 16 August 2019Source: Sensors and Actuators A: PhysicalAuthor(s): Weina Liu, Xinwei Yang, Youtian Niu, Haoran SunAbstractIn this paper, a sub-wavelength resonance sensor is proposed to microwave detection applications. A meta-material element—multiple split ring resonator (MSRR) is used to improve the sensitivity of the sensor. Therefore, the sensor is based on micro-strip technology and consists of a micro-strip and a MSRR. It is observed that the strongest electric field of the sensor can achieve to 105V/m. So the sensor is very sensitive to capture changes of dielectric signals. ...
Source: Sensors and Actuators A: Physical - Category: Physics Source Type: research
Authors: Karabay O, Güçlü E, Şimşek A, Okan HD, Öğütlü A, Coşgun Y, Menemenlioğlu D Abstract The frequency of travel-related infections in the world has increased due to the easily and widespread use of travel facilities in the 21st century. Vector-borne diseases are an important part of infectious diseases. Dengue fever is one of the travel-related infections that has been reported increasingly in recent years through the development of diagnostic methods. The aim of this report was to present two Dengue fever cases originating from travel. There was a story of mosquito bite du...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
In conclusion, it is recommended that in addition to direct microscopic examination, the use of additional methods such as culture and PCR will be useful in routine laboratory diagnosis of Blastocystis spp. The distribution of Blastocystis subtype in Aydin is mainly in accordance with the global findings. Lack of a relationship between Blastocystis spp. İnfection and symptoms in our study was supported the idea that Blastocystis spp. infection is mostly asymptomatic in humans and it may be a member of healthy microbiota. PMID: 31414632 [PubMed - in process]
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
In this study, the prevalence of adenoviral conjunctivitis determined by hexon gene PCR in patients with clinical diagnosis of acute conjunctivitis was similar to the prevalence rate reported in other regions of the world. In our region, more than one type of hAdV type was associated with acute conjunctivitis. The predominant type was determined as hAdV-8 with a 63% ratio. These results will significantly contribute to the molecular epidemiology of hAdV types in conjunctivitis cases. PMID: 31414631 [PubMed - in process]
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
In this study, it was aimed to evaluate 195 patients (119 urban and 76 rural residents, 121 female and 74 male individuals between 18 and 93 years of age) in terms of gastric Helicobacter (H.pylori, H.felis and H.heilmanii) who have admitted to the Health Research and Application Center of Kafkas University Endoscopy Unit of the General Surgery Department with the complaints of abdominal pain. For this purpose, biopsy specimens obtained from various parts of the stomach (corpus and antrum) by endoscopy were analyzed with histopathological examination and PCR. Histopathological analysis sections were stained with May-Grunwa...
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
Publication date: Available online 16 August 2019Source: Molecular and Cellular ProbesAuthor(s): Ping Zhou, Guoyang Xie, Taobo Liang, Bei Yu, Zoraida Aguilar, Hengyi XuAbstractEmetic Bacillus cereus is one of the causative agents of foodborne diseases which can cause vomiting-type food poisoning after ingestion of contaminated food. To minimize B. cereus food poisoning, propidium monoazide (PMA) combined with quantitative polymerase chain reaction (qPCR) called PMA-qPCR was applied for detecting viable emetic B. cereus in milk. The cereulide synthetase gene of emetic B. cereus (cesB) was chosen for the primer, and PMA trea...
Source: Molecular and Cellular Probes - Category: Molecular Biology Source Type: research
Publication date: Available online 16 August 2019Source: Molecular and Cellular ProbesAuthor(s): Yan Li, Min Mao, Hong Liu, Xiaomin Wang, Zhen Kou, Yuling Nie, Yichun Wang, Zengsheng Wang, Qin Huang, Tao Lang, Zailinuer Gu, Li An, Xiaoyan Zhang, Lin FuAbstractThe abnormal expression of miRNAs may play critical roles in the occurrence, development and prognosis of chronic lymphocytic leukemia (CLL), with potential ethnic differences being involved. p53 and immunoglobulin heavy chain variable region gene (IGVH) mutations were monitored and miRNA profile screening of CD19 + cells from Uygur CLL patients was performed, ana...
Source: Molecular and Cellular Probes - Category: Molecular Biology Source Type: research
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