Duration of infertility in men may affect sperm count

(Wiley) A longer duration of infertility was associated with lower sperm count and other parameters of impaired sperm in a BJU International study of 1644 infertile men. Also, older age and higher body mass index were associated with a longer duration of infertility.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Conclusion Material and MethodsTheca cells, collected from normal cycling and PCOS patient underwent ovariectomy, were seeded on culture dishes pre-coated with the extracellular matrix at a density of 6 × 104 cells/ml and cultured for 24 hours. Cells were then treated with either 3T3 conditioned media as a control (C) or Mesenchymal stem cells conditioned media (CM). The C and CM were prepared through collecting the serum-free supernatant of 3T3 and hMSCs at an optimal confluence, 48 hours later. The mRNA and protein expression of CYP17A1, CYP11A1, and DENND1A.V2 were quantified by RT-PCR and Western blot, while ...
Source: Cytotherapy - Category: Cytology Source Type: research
Conclusions: The results of this meta-analysis suggest that SERMs may be effective in the treatment of infertile patients with idiopathic infertility. However, the paucity of data does not allow to draw a definitive conclusion. PMID: 31120775 [PubMed - as supplied by publisher]
Source: Expert Opinion on Pharmacotherapy - Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Condition:   Patient Satisfaction Intervention:   Other: EngagedMD online learning platform Sponsor:   University of North Carolina, Chapel Hill Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsIn combination, the studies discussed, as well as two recent projects of our own on placental imprinted gene expression, suggest that lower birthweights in IVF infants are secondary to a combination of exposures including the infertility and prenatal stress that couples undergoing IVF are experiencing. The work highlighted herein emphasizes the need for appropriate control populations that take infertility into account and also for consideration of prenatal psychosocial stressors as confounders and causes of variation in IVF infant outcomes.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research
Abstract Considering that myths and misconceptions regarding natural procreation spread rapidly in the era of easy access to information and to social networks, adequate counseling about natural fertility and spontaneous conception should be encouraged in any kind of health assistance. Despite the fact that there is no strong-powered evidence about any of the aspects related to natural fertility, literature on how to increase the chances of a spontaneous pregnancy is available. In the present article, the Brazilian Federation of Gynecology and Obstetrics Associations (FEBRASGO, in the Portuguese acronym) Committee on Endoc...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Conditions:   Male Infertility;   Infertility, Male Interventions:   Other: MicroFluidic Sperm Sorting Chips;   Other: Gradient-Density Centrifugation Sponsors:   Bezmialem Vakif University;   Yeditepe University Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 21 May 2019Source: Preventive Veterinary MedicineAuthor(s): P.R. Hut, A. Mulder, J. van den Broek, J.H.J. L. Hulsen, G.A. Hooijer, E.N. Stassen, F.J.C.M. van Eerdenburg, M. NielenAbstractIn dairy cattle, reproductive diseases and infertility are some of the most important reasons for culling, where postpartum negative energy balance (NEB) reduces reproductive performance. This single cohort observational study reports the association between eating time and the interval between calving and first service in 2036 dairy cows on 17 commercial farms in The Netherlands. Cows were equipped with ...
Source: Preventive Veterinary Medicine - Category: Veterinary Research Source Type: research
This study aimed to evaluate the effect of fenugreek seed aqueous (FSA) extract on serum E2 levels in a rat model of OHSS. Methods: A total of 34 female Sprague Dawley rats, aged 18 days old, weighing 40 to 45 g, were randomly divided into negative control, positive control, and treatment groups. A daily dose of 1500 mg/kg per body weight of FSA extract was administrated orally to rats in the treatment group for 13 days. On day eight of the study, OHSS was induced in both positive control and treated groups by subcutaneous injection of pregnant mare's serum gonadotropin 50 IU for four consecutive days, followed by huma...
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
ConclusionsIt is safe and effective for early-stage patients with cervical cancer whose lesions are less than 2  cm to receive RVT. For those patients with lesions 2–4 cm who desire fertility preservation and without any evidence of infertility, RAT can be a feasible alternative to RH under fully informed consent. However, more CCTs with larger sample size are still required for further validation.
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
AbstractPurposeThe aim of the present study was to evaluate the effect of myo-Inositol administration on oocyte quality, fertilization rate and embryo quality in patients with PCOS during assisted reproductive technology (ART) cycles.MethodsFifty infertile PCOS patients were randomly designated in two groups. In the study group, patients received daily doses of 4  g myo-Inositol combined with 400 mg folic acid and in the control group patients received only 400 mg folic acid from 1 month before starting the antagonist cycle until the day of ovum pick up. Oocyte and embryo qualities were assessed according to...
Source: Archives of Gynecology and Obstetrics - Category: OBGYN Source Type: research
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