Haemodynamic effects of pharmacologic stress with adenosine in patients with left ventricular systolic dysfunction

In patients with heart failure, downregulation of adenosine receptor gene expression and impaired adenosine-related signal transduction may result in a diminished response to adenosine. This may have implications for cardiac stress testing. We evaluated the haemodynamic response to intravenous adenosine in patients with left ventricular systolic dysfunction (LVSD) undergoing stress cardiovascular magnetic resonance imaging (CMR).

Source: International Journal of Cardiology - December 4, 2018 Category: Cardiology Authors: Gaurav S. Gulsin, Ahmed M.S.E.K. Abdelaty, Abhishek Shetye, Florence Y. Lai, Amrita Bajaj, Indrajeet Das, Aparna Deshpande, Praveen P.G. Rao, Jeffrey Khoo, Gerry P. McCann, Jayanth R. Arnold Source Type: research