Biochemical and physiological responses of Nile tilapia ( Oreochromis niloticus Linn.) subjected to rapid increases of water temperature

AbstractThis research evaluated the general stress response, serum biochemistry, hematology, cortisol level, and ventilation rates of the commercial fresh water fishOreochromis nilotichus, which was subjected to acute heat shock treatment. The consequences of heat shock were evaluated using five different water temperature levels (25  °C used as the control group, then 27 °C, 29 °C, 33 °C, and 37 °C, the rate was increased 3 °C per hour). All serum indices showed significant changes (p 
Source: Comparative Clinical Pathology - Category: Pathology Source Type: research

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ConclusionIn conclusion, G. procumbens ethanol extract and its fractions inhibit the formation of macrophage derived foam cell by reducing TNF-α and IL-1β expression, which usually highly expressed in atherosclerotic plaques, suppressing scavenger receptor LOX-1 gene that binds oxLDL but induced ABCA-1 gene that mediate lipid efflux from macrophages.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
This study aimed to investigate the anti-obesity effects of ginseng and the alternation of gut microbiota composition in high-fat diet (HFD)-induced obesity. The results showed that HFD treatment influenced body weight gain, adipose tissue accumulation and biochemical parameter changes. Compared to the HFD group, ginseng supplementation of HFD-fed mice decreased body weight, adipose tissue mass, total cholesterol (T-CHO) and high-density lipoprotein (HDL)/low-density lipoprotein (LDL) ratio. To analysis the alterations of gut microbiota, ginseng in dietary supplements decreased Firmicutes abundance and increased Bacteroide...
Source: Food Science and Human Wellness - Category: Food Science Source Type: research
Publication date: Available online 16 November 2019Source: Biocatalysis and Agricultural BiotechnologyAuthor(s): Anil Kumar Singh, Himanshu Pandey, Pramod W. Ramteke, Shanti Bhushan MishraAbstractUrsolic acid is a pentacyclic carboxylic acid present in medicinal herbs abundantly. There is scientific evidence of important benefits of ursolic acid in metabolism of lipids and glucose, as well as on the body weight and metabolic parameters. However, the hydrophobicity of ursolic acid increases the difficulty in its potential clinical application. The aim of the present study is to develop ursolic acid nanoparticles to enhance ...
Source: Biocatalysis and Agricultural Biotechnology - Category: Biotechnology Source Type: research
Publication date: Available online 16 November 2019Source: Carbohydrate PolymersAuthor(s): E.V. Sokolova, A.O. Kravchenko, N.V. Sergeeva, V.N. Davydova, L.N. Bogdanovich, I.M. YermakAbstractThe research described here focused on the effect of sulfated red algal polysaccharides (κ-, κ/β-, ι/κ-carrageenan) individually and in combination with lipopolysaccharide (LPS) on the synthesis of prostaglandin E2 (PGE2) and cytokines (interleukin [IL]-1β and IL-6) in whole blood model in vitro. The results demonstrated that, at high concentrations, carrageenans have substantial ability to modulate PGE2...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
ConclusionsPoor SRH was associated with raised concentrations of many plasma proteins. However, the relationships were largely attenuated by adjustments for CVD risk factors, comorbidity and psycho-social factors. Leptin and CCL20 were associated with poor SRH in the present study and could potentially be involved in the SRH –CVD link.
Source: Clinical Proteomics - Category: Biochemistry Source Type: research
ConclusionThese results support the conclusion that FGIN ‐1‐27 stimulates steroid formation by increasing TSPO‐mediated cholesterol translocation into the inner mitochondria for steroidogenesis, as well as into the cytosol for lipid droplet formation. FGIN‐1‐27 also increased steroid formation at least in part by inducing the conversion of chole steryl ester located in lipid droplets to cholesterol, thus making available more substrate for steroid formation.
Source: Andrology - Category: Urology & Nephrology Authors: Tags: ORIGINAL ARTICLE Source Type: research
AbstractThe current study was carried out to determine the changes in serum electrolytes, liver enzymes, and hormones during breeding and non-breeding seasons in estrus-synchronized goats. Forty goats (n = 40) were synchronized by inserting the sponges intravaginally for 12 days; PMSG and PGF2α were injected on day of sponge removal. Blood samples were collected from the goats at the time of sponges insertion (day -12), estrus day (day 0), and at 15 day after sponge withdrawal (day 15). The blood samples were analyzed for glucose, cholesterol (CHO), aspartate aminotransferase (AST), al anine ami...
Source: Tropical Animal Health and Production - Category: Veterinary Research Source Type: research
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
A second phase 3 study has shown impressive reductions in LDL on top of statins with this novel agent given just twice a year.Medscape Medical News
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Cardiology News Source Type: news
The proprotein convertase subtilisin/kexin type 9 inhibitor alirocumab significantly reduces low-density lipoprotein cholesterol (LDL-C).
Source: Journal of Clinical Lipidology - Category: Lipidology Authors: Tags: Original Research Source Type: research
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