Clinical evidence for dose tolerance of the central nervous system in hypofractionated radiotherapy

ConclusionsEffective differences between single fraction SRS and conventional radiotherapy need to be better understood. The existing biological model might not be valid to predict the radiosurgical outcomes based on conventionally fractionated radiotherapy. However, application of the statistical dose response models of clinical SRS and SBRT outcomes data to selected current dose tolerance guidelines into simple tables can be a clinically useful resource.
Source: Journal of Radiation Oncology - Category: Cancer & Oncology Source Type: research