Characterization of 3 Novel Tau Radiopharmaceuticals, 11C-RO-963, 11C-RO-643, and 18F-RO-948, in Healthy Controls and in Alzheimer Subjects
Conclusion: 18F-RO-948 demonstrates characteristics superior to 11C-RO-643 and 11C-RO-963 for characterization of tau pathology in AD. Regional binding data and kinetic properties of 18F-RO-948 compare favorably with other existing tau PET tracers.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Wong, D. F., Comley, R. A., Kuwabara, H., Rosenberg, P. B., Resnick, S. M., Ostrowitzki, S., Vozzi, C., Boess, F., Oh, E., Lyketsos, C. G., Honer, M., Gobbi, L., Klein, G., George, N., Gapasin, L., Kitzmiller, K., Roberts, J., Sevigny, J., Nandi, A., Bras Tags: Translational Source Type: research
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