Low maternal thyroxine during early gestation and offspring schizophrenia in a national birth cohort

Background: Evidence from animal and human studies indicates that thyroid hormone deficiency during early gestation alters brain development. As schizophrenia is associated with prenatal brain insults and premorbid cognitive deficits, we tested the a priori hypothesis that serologically defined maternal thyroid deficiency during early gestation is associated with offspring schizophrenia.
Source: Comprehensive Psychiatry - Category: Psychiatry Authors: Source Type: research