Management of thyrotoxicosis in children and adolescence: a Turkish multi-center experience.

CONCLUSION: This study demonstrated that using anti-thyroid drugs with the hope that the patients will enter a remission over time is generally accepted first-line approach in Turkish children and adolescents with GD, however, this approach achieved low remission rate which was consistent with previous studies. PMID: 30488822 [PubMed - as supplied by publisher]
Source: JCRPE Journal of Clinical Research in Pediatric Endocrinology - Category: Endocrinology Tags: J Clin Res Pediatr Endocrinol Source Type: research

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ConclusionsAERP shortening due to altered protein levels of ion channels and atrial structural changes increased the susceptibility to AF in hypothyroidism. Thyroid replacement therapy could prevent electrical and structural remodeling under hypothyroid condition.
Source: Endocrine - Category: Endocrinology Source Type: research
This study aims at whether thyroid function has an effect on the 18F-FDG uptake in these reference organs on 18F-FDG PET/CT imaging. Materials and Methods: A total of 69 patients were included in this study for retrospective analysis. All of these patients had a thyroidectomy history,30of 69 patients were undergoing thyroid hormone replacement therapy,39 of 69 patients were not. All patients fasted for at least 6-8 h before PET-CT imaging and their fasting blood glucose levels were within the normal range. Image acquisition was performed after intravenous administration of 18F-FDG. Two groups were defined according to the ...
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Endocrine (GCS) Posters Source Type: research
CONCLUSIONS: REE, REE/LBM, pulse, and systolic and diastolic blood pressure were significantly higher after thyroidectomy, radioiodine and TSH suppressive therapy in female DTC patients, while no changes were observed in body weight or body composition. A lower TT3/FT4 ratio longitudinally correlated with increases in REE, REE/LBM, abdominal fat distribution, systolic blood pressure and fasting blood glucose, as well as with decreased RQ. These findings highlight the importance of judicial balancing of the benefits and detriments of TSH suppression with subsequent decreased TT3/FT4 ratios for female DTC patients. PMID:...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
Abstract Colorectal cancer (CRC) is the second leading cause of cancer-related death. The prevalence of colorectal neoplasm is increasing. Many studies have shown that thyroid dysfunction may be connected with the higher risk of pancreatic and breast cancer, but only a few described the role of thyroid dysfunction and thyroid hormone (TH) replacement in the development and risk of CRC. The aim of this study is to summarise all findings and potentially elucidate the connection between TH imbalance and colorectal cancer. The systematic review was conducted according to PICO and PRISMA guidelines. We searched MEDLINE...
Source: Endokrynologia Polska - Category: Endocrinology Authors: Tags: Endokrynol Pol Source Type: research
Marco Vacante1, Antonio Biondi1, Francesco Basile1, Roberto Ciuni1, Salvatore Luca1, Salomone Di Saverio2, Carola Buscemi3, Enzo Saretto Dante Vicari3 and Antonio Maria Borzì3* 1Department of General Surgery and Medical-Surgical Specialties, University of Catania, Catania, Italy 2Cambridge Colorectal Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom 3Department of Clinical and Experimental Medicine, Specialization School in Geriatrics, University of Catania, Catania, Italy There is a high prevalence of hypothyroidism in the elderly population, mainly among women. The mo...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Authors: Patel A, Shostrom V, Treude K, Lydiatt W, Smith R, Goldner W Abstract Objective: We evaluated if preoperative TG levels affected postoperative levels and if other factors may influence the optimal time to check postoperative TG. Methods: This is a prospective, observational pilot study. We approved and enrolled 50 subjects ≥ 19 years scheduled for total thyroidectomy and measured serum TG, thyroglobulin antibody (TG ab), and TSH preoperatively and post thyroidectomy at 7-14 days, 4 and 6 weeks, and 3 months in subjects with benign pathology, with additional 6- and 12-month measurements in subjects w...
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
Horm Metab Res DOI: 10.1055/a-0739-8134The course and pathogenesis of Graves’ disease and Graves’ ophthalmopathy are interdependent, influencing each other’s therapeutic choices. Multiple factors including geographic location, access to medical services, patient and physician preferences influence the management of these conditions. Graves’ disease is classically managed with one of three treatment options – antithyroid drugs, radioactive iodine, and thyroidectomy. In recent years, there has been a shift towards antithyroid drugs, including long term therapy with these agents, given the advant...
Source: Hormone and Metabolic Research - Category: Endocrinology Authors: Tags: Review Source Type: research
CONCLUSIONS Hyperthyroidism increases the risk of CVD-related hospitalization, and the risk is sustained for up to two decades after treatment with RAI or surgery. Hyperthyroid patients treated with RAI remain at a higher CVD risk compared to patients treated with thyroidectomy. Hypothyroidism during the follow-up, however, predicts better cardiovascular outcome. PMID: 29882483 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
CONCLUSION: Thyroid gland suppuration is a very infrequent circumstance in neck pathology, and the options for its treatment are varied, from conservative to invasive techniques according to the microbial and radiologic findings. PMID: 29891396 [PubMed - as supplied by publisher]
Source: Acta Otorrinolaringologica Espanola - Category: ENT & OMF Authors: Tags: Acta Otorrinolaringol Esp Source Type: research
Although the mechanism in which thyroid gland dysfunction affects keratoconus is not known, evidence is mounting that an association exists between thyroid hormone alterations and keratoconus disease progression. Previous case reports described keratoconus developing after surgical thyroidectomy,1 acute severe hydrops in a child with Down syndrome and hyperthyroidism,2 acute deterioration of keratoconus induced by hypothyroxemia during pregnancy,3 bilateral keratoconus associated with Hashimoto's disease,4 and keratoconus associated with Alagille syndrome and secondary hypothyroidism.5 In
Source: Journal of Refractive Surgery - Category: Opthalmology Authors: Source Type: research
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