Green Synthesis of Phosphoryl-2-oxo-2H-Pyran Via Three Component Reaction of Trialkyl Phosphites.
Green Synthesis of Phosphoryl-2-oxo-2H-Pyran Via Three Component Reaction of Trialkyl Phosphites.
Comb Chem High Throughput Screen. 2014 Nov 6;
Authors: Hossaini Z, Sheikholeslami-Farahani F, Rostami-Charati F
Abstract
An effective one-pot synthesis of dialkoxyphosphoryl-2-oxo-2H-pyran derivatives by three-component reaction of alky bromides and dialkyl acetylenedicarboxylates in the presence of trialkyl phosphite is described. The reactions were performed under solvent-free conditions at 50oC and neutral conditions and provided good yields of products.
PMID: 25373506 [PubMed - as supplied by publisher]
Source: Combinatorial Chemistry and High Throughput Screening - Category: Chemistry Authors: Hossaini Z, Sheikholeslami-Farahani F, Rostami-Charati F Tags: Comb Chem High Throughput Screen Source Type: research
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