Serum markers in the differential diagnosis of Waldenstrom macroglobulinemia and other IgM monoclonal gammopathies.

CONCLUSIONS: The five serum markers, LDH, IgM, IgG, IgA, and К, each yielded a specific efficacy in differential diagnosis of WM. The single marker with the highest diagnostic efficiency was the serum IgM level. However, a combination of multiple serum markers was better than the use of a single marker in diagnosing WM. The combined use of all five serum markers provided the most effective diagnosis, with an AUC of .952 and sensitivity and specificity of 87.8% and 86.9%, respectively. PMID: 30485557 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30485557?dopt=Abstract

Source: Clinical Lymphoma and Myeloma - November 28, 2018 Category: Cancer & Oncology Authors: Zou H, Yang R, Liao ZX, Qin TD, Chen P, Zhang BY, Cao YP, Huang HF Tags: J Clin Lab Anal Source Type: research