FAM3B (PANDER) functions as a co-activator of FOXO1 to promote gluconeogenesis in hepatocytes.

In conclusion, PANDER protein is abundantly present in the nucleus, where it functions as a new co-activator of FOXO1 to induce gluconeogenic gene expression in hepatocytes.
PMID: 30488666 [PubMed - as supplied by publisher]

Source: J Cell Mol Med - November 28, 2018 Category: Molecular Biology Authors: Chi Y, Meng Y, Wang J, Yang W, Wu Z, Li M, Wang D, Gao F, Geng B, Tie L, Zhang W, Yang J Tags: J Cell Mol Med Source Type: research