Treprostinil treatment decreases circulating platelet microvesicles and their procoagulant activity in pediatric pulmonary hypertension

ConclusionOur results suggest that treprostinil, besides vasodilation, might exert its beneficial effect through an inhibition of platelet activation, resulting in a decreased number and procoagulant activity of circulating MVs.

Source: Pediatric Pulmonology - November 28, 2018 Category: Respiratory Medicine Authors: Nour C. Bacha, Marilyne Levy, Coralie L. Guerin, Bernard Le Bonniec, Annie Harroche, Isabelle Szezepanski, Jean M. Renard, Pascale Gaussem, Dominique Israel ‐Biet, Chantal M. Boulanger, David M. Smadja Tags: ORIGINAL ARTICLE: PULMONARY HYPERTENSION Source Type: research