Febrile Hypotensive Reactions Following ABVD Chemotherapy in Patients with EBV Associated Classical Hodgkin ’s Lymphoma

ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) is a widely used frontline regimen for the treatment of early and advanced stage classical Hodgkin ’s lymphoma (cHL). A fulminant syndrome characterized by pyrexia and shock was observed in early trials of bleomycin, occurring more frequently in patients with lymphoma. In the past three decades, only one case of a similar fulminant reaction following ABVD has been reported and thus there is lim ited literature regarding the risk factors, clinical course, and management for this life threatening syndrome.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Tags: Case Report Source Type: research